| |

Muscle Wasting / Muscle Atrophy

Byepsuadmin

One can appreciate from this photo that there is significant lower limb wasting (or muscle atrophy) of the right leg compared to the left. The right leg is also shorter compared to the left. Muscle wasting (or atrophy) is due to denervation of the muscle supplied by the motor nerve and occurs in lower motor neuron lesions, i.e. a lesion that either involves the anterior horn cell, or distal to the anterior horn cell (e.g. nerve root, plexus or peripheral nerve).

Similar Posts

  • |

    Encephalitis

    Byepsuadmin

    A. Clinical manifestations The clinical manifestations of encephalitis may be similar to those of meningitis. However, altered level of consciousness is a predominant sign. It can range from mild lethargy to deep coma. Moreover, focal or generalized seizures occur in many patients with encephalitis, especially in severe disease. Virtually every possible type of focal neurological…

  • |

    CSF Shunt Infection

    Byepsuadmin

    A. Clinical manifestations The clinical features of CSF shunt infection can be quite variable and depend on the pathogenesis of the infection, organism virulence and type of shunt. The most frequent symptoms are headache, nausea, lethargy, fever and change in mental status. Pain, often related to infection at the peritoneal or pleural endings of the…

  • Arterio-venous Malformations

    Byepsuadmin

    Cerebral vascular malformations can be classified by histopathology into 4 major types: Arterio-venous malformations (AVMs) Venous angiomas (developmental venous anomalies) Capillary telangiectasias and Cavernous malformations Arterio-venous malformations (AVMs) are congenital vascular lesions due to dysregulated angiogenesis. They are most often solitary but rarely could be multiple, in which case an underlying syndrome (e.g. hereditary haemorrhagic telangiectasia,…

  • Vascular Dementia

    Byepsuadmin

    Vascular dementia is the second most common cause of dementia and accounts for approximately 10% of all dementias in developed countries. The incidence of vascular dementia increases with age and are associated with common cardiovascular risk factors (hypertension, diabetes, dyslipidaemia etc.). Patients often present with a sudden, stepwise, neurological deterioration and there may be other…

  • Thymoma

    Byepsuadmin

    In this contrast thoracic CT scan of a middle-aged woman with newly diagnosed seropositive generalized myasthenia gravis, an abnormal thymic lesion (present in the anterior mediastinal compartment) could be seen  (Figure 1). The patient was referred to the Cardiothoracic Surgeons where she received a thymectomy via an open sternotomy. The thymic specimen was sent for histo-pathological…