The set of cranial MRIs shown here are from a young woman with a known history of relapsing-remitting multiple sclerosis. In the first scan (T2W axial cut), we can see multiple T2 hyperintense lesions involving bilateral cerebral cortices (Figure 1). These lesions are noted to be of a juxta-cortical and also peri-ventricular distribution, which are classical of multiple sclerosis. In the next…
In this contrast thoracic CT scan of a middle-aged woman with newly diagnosed seropositive generalized myasthenia gravis, an abnormal thymic lesion (present in the anterior mediastinal compartment) could be seen (Figure 1). The patient was referred to the Cardiothoracic Surgeons where she received a thymectomy via an open sternotomy. The thymic specimen was sent for histo-pathological…
A lumbar puncture (LP, also known as a spinal tap) is a diagnostic and at times, therapeutic medical procedure. Diagnostic indications The main diagnostic indications of performing a LP is for collection and evaluation of cerebrospinal fluid (CSF) for diagnosis and exclusion of infectious, inflammatory and neoplastic diseases affecting the central nervous system. For example,…