Wilson’s disease

A number of systemic conditions can cause corneal problems. Rheumatological conditions, in particularly rheumatoid arthritis, can cause a peripheral thinning of the cornea called peripheral ulcerative keratitis. If untreated, this can lead to perforation of the cornea and loss of integrity of the globe. Other examples include systemic lupus erythematosus, Wegener’s granulomatosis and polyarteritis nodosa….