Examining the Sensory System
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Subtitles in English for this video can be displayed by clicking on (first button on the bottom right hand corner of the video).
A. Clinical manifestations The clinical manifestations of encephalitis may be similar to those of meningitis. However, altered level of consciousness is a predominant sign. It can range from mild lethargy to deep coma. Moreover, focal or generalized seizures occur in many patients with encephalitis, especially in severe disease. Virtually every possible type of focal neurological…
This coronal FLAIR MRI is from an 18 year old man who presented with a 5-year history of temporal lobe epilepsy. He would present with an epigastric aura, describing it as a strange feeling which ascends from the stomach, and there will sometimes be an accompanying sense of fear. The patient would subsequently be noted…
Dementia with Lewy bodies is the second most common neurodegenerative dementia after Alzheimer’s disease, accounting for 15-20% of all cases. This form of dementia is due to an abnormal accumulation of Lewy bodies, which are spherical intra-neuronal protein aggregates consisting primarily of α-synuclein. Dementia with Lewy bodies is therefore considered as a synucleinopathy. Other synucleinopathies…
The scans shown are from two immunocompromised patients who presented with high fever and recurrent seizures. The contrast cranial CT of the first patient shows that the patient had a rim-enhancing lesion at the left basal ganglia (Figure 1). A set of cranial MRIs of the second patient also showed multiple contrast enhancing lesions in the…
Normal Cerebrospinal Fluid The photos shown here is that of normal cerebrospinal fluid after a lumbar puncture. Normal cerebrospinal fluid is colourless and odorless. Xanthochromia The cerebrospinal fluid here shows xanthochromia (Figure 1), meaning of yellow discolorization. Presence of xanthrochromia means that there is presence of red cells in the cerebrospinal fluid. With time, the red…
These two videos are from a middle-aged man presenting with progressive bilateral lower limb and right upper limb weakness for few months. In the first video, there are prominent fasciculations over the entire right upper limb. Whilst in the second video, fasciculations can also be noted over both lower limbs, but more prominent on the…