The scans shown are from two immunocompromised patients who presented with high fever and recurrent seizures. The contrast cranial CT of the first patient shows that the patient had a rim-enhancing lesion at the left basal ganglia 
(Figure 1). A set of cranial MRIs of the second patient also showed multiple contrast enhancing lesions in the right basal ganglia and also a larger one at the left parietal lobe (Figures 2 and 3).
A middle-aged woman was admitted with drowsiness, weakness of all four limbs and visual impairment. Physical examination revealed that the patient had bilateral complete ophthalmoplegia, generalized weakness and spasticity,with brisk reflexes and bilateral upgoing plantar reflexes. A hyper-intense lesion at the level of the midbrain was noted on cerebral MRI (Figure 1). Cerebro-spinal fluid examination…
Cerebral vascular malformations can be classified by histopathology into 4 major types: Arterio-venous malformations (AVMs) Venous angiomas (developmental venous anomalies) Capillary telangiectasias and Cavernous malformations Arterio-venous malformations (AVMs) are congenital vascular lesions due to dysregulated angiogenesis. They are most often solitary but rarely could be multiple, in which case an underlying syndrome (e.g. hereditary haemorrhagic telangiectasia,…
There are a number of causes of spontaneous parenchymal haemorrhages. These include: hypertension, vascular malformations and aneurysms, neoplasm (primary or metastatic), cerebral amyloid angiopathy, use of antiplatelet agents or anti-coagulants, blood dyscrasias and drug abuse (e.g. amphetamine and cocaine use). Parenchymal haemorrhages could also be subdivided into deep versus lobar haemorrhages, where deep haemorrhages (basal ganglia, thalamus,…
This cranial MRI is from a young woman who presented with low-grade fever, confusion, visual hallucinations and status epilepticus. Significant orofacial dyskinesias and autonomic dysfunction was also noted. Lumbar puncture was performed and cerebrospinal fluid (CSF) revealed mild lymphocytic predominant leukocytosis and slightly elevated protein. CSF glucose was within normal range and CSF for microbiological…
In this contrast thoracic CT scan of a middle-aged woman with newly diagnosed seropositive generalized myasthenia gravis, an abnormal thymic lesion (present in the anterior mediastinal compartment) could be seen (Figure 1). The patient was referred to the Cardiothoracic Surgeons where she received a thymectomy via an open sternotomy. The thymic specimen was sent for histo-pathological…
This is a non-contrast cranial CT from a patient who sustained a fall injury, landing on the back of the head. The CT here shows the cranium utilizing the “bone window”. One can appreciate that the details of the skull bone is shown in greater detail. In contrast, the contents within the skull as well…